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Ethnobotanical Studies of Medicinal Plants Used in Managing Diabetes mellitus in Rejang Lebong Districts, Bengkulu – Indonesia

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Sri Endarti Rahayu, Yusi Marisa, Ikhsan Matondang ABSTRACT Diabetes mellitus is becoming a major cause of concern throughout the world. Many people, especially in rural communities, use medicinal plants to treat the disease and its complications. This study aimed to document the medicinal plant species used to manage diabetes mellitus and traditional knowledge of local … Read more

Ethnobotany Survey of Medicinal Plants Used for Traditional Maternal Healthcare by Serawai Tribe, Seluma District, Bengkulu-Indonesia

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Sri Endarti Rahayu, Rika Oktapianti, Ikhsan Matondang ABSTRACT Background and objective: Ethnomedicine plays an important role in the maternal healthcare practice of the Serawai tribe of Seluma district, Bengkulu, however, itsuse has never been documented. This study, therefore, conducts an ethnobotanical survey to document the medicinal plant used for traditional maternal healthcare inthe Serawai tribe. … Read more

Efektivitas Suplementasi Ekstrak Daging Ikan Bujuk (Channa Lucius) dalam Mempercepat Penyembuhan Luka Diabetik

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Ernawati Sinaga, Suprihatin, Fitri Istiqomah ABSTRAK Luka diabetik adalah salah satu komplikasi kronis penyakit diabetes melitus yang sangat ditakuti, karena dapat membawa kecacatan seumur hidup bahkan kematian. Jumlah penderita diabetes semakin meningkat. Penelitian ini dilakukan untuk membuktikan efektivitas suplementasi ekstrak daging ikan bujuk dalam mempercepat penyembuhan luka diabetik. Penelitian dilakukan menggunakan tikus putih jantan galur … Read more

Evaluation of Antioxidant and Antidiabetic Activities from Red Seaweed (Eucheuma cottonii) Extract

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Vivitri Dewi Prasasty, Benedicta Haryani, Rory Anthony Hutagalung, Noryawati Mulyono, Fatmawati Yazid, Rosmalena Rosmalena, Ernawati Sinaga ABSTRACT Diabetes mellitus is a chronic disorder of metabolic characterized by high blood sugar levels (hyperglycemia) and glucose secretion in urine caused by lack of insulin. Hyperglycemia can cause free radical molecules formation, which can be stabilized by antioxidants. … Read more

Antihyperglycemic and Antihyperlipidemic Effects of Methanolic Seeds Extract of Pandanus odoratissimus in Alloxan-Induced Diabetic Rats

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Sri Endarti Rahayu, Ernawati Sinaga, Suprihatin, Arief Dwi Jayanto, Yedi Adistron ABSTRACT Diabetes mellitus is one of the most serious diseases affecting a larger global population, accompanied with other long-term complications. Also, the management is this disease comes with various side effects, hence, the need for substances with little or no side effect. Therefore, this … Read more

Structure-based discovery of novel inhibitors of Mycobacterium tuberculosis CYP121 from Indonesian natural products

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Vivitri Dewi Prasasty, Sandra Cindana, Fransiskus Xaverius Ivan, Hilyatuz Zahroh, Ernawati Sinaga ABSTRACT Tuberculosis (TB) continues to be a serious global health threat with the emergence of multidrug-resistant tuberculosis (MDR-TB) and extremely drug-resistant tuberculosis (XDR-TB). There is an urgent need to discover new drugs to deal with the advent of drug-resistant TB variants. This study aims to find new … Read more

Effect of supplementation of Rhodomyrtus tomentosa fruit juice in preventing hypercholesterolemia and atherosclerosis development in rats fed with high fat high cholesterol diet

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Ernawati Sinaga, Suprihatin, Yenisbar, Mardian Iswahyudi, Sarwi Setyowati, Vivitri D. Prasasty ABSTRACT Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Nutraceuticals, mainly based on natural products, have been proven to control the risk factors of CVDs effectively. Rhodomyrtus tomentosa is an underutilized fruit that is rich in phenolic compounds and has antioxidant activities. Scientific investigation was needed to … Read more

Sambiloto (Andrographis paniculata)

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 By Ernawati Sinaga Sambiloto adalah salah satu tumbuhan obat Indonesia yang sangat populer. Selain sambiloto, tumbuhan ini juga dikenal dengan nama Pepaitan (Sumatera), Ki oray, ki peurat, takila (Sunda), atau takilo (Jawa), xuyen tam lien, cong cong (Vietnam), kirata, mahatitka (India/Pakistan), chuan xin lian, yi jian xi, lan he lian (China), atau creat, green chiretta, halviva, … Read more

Hepatoprotective Effect of Pandanus Odoratissimus Seed Extracts on Paracetamol-Induced Rats

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Ernawati Sinaga, Ami Fitrayadi, Asrori Asrori, Sri Endarti Rahayu, Suprihatin Suprihatin, Vivitri Dewi Prasasty ABSTRACT Context: Pandanus Odoratissimus Linn. (Pandanaceae) seed extract is known to have antioxidant activities. However, the potential hepatoprotective effect is still unclear. Objective: To investigate the hepatoprotection aspect of P. odoratissimus methanol extract towards paracetamol-induced rats. Materials and methods: Thirty male Sprague–Dawley rats were randomly divided … Read more

Karamunting (Rhodomyrtus tomentosa)

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Tanaman Karamunting

By Ernawati Sinaga Karamunting has many local names, e.g. Masisin in Central Kalimantans, Kemunting in Malaysian and Rose Myrtle or Downy Myrtle in English. Sometimes it is mistaken for the more common Senduduk (Melastoma malabathricum). However, these two berries are not closely related, because Senduduk belongs to Melastomataceae family while Karamunting belongs to Myrtaceae. This dark … Read more

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