Efektivitas Suplementasi Ekstrak Daging Ikan Bujuk (Channa Lucius) dalam Mempercepat Penyembuhan Luka Diabetik

Ernawati Sinaga, Suprihatin, Fitri Istiqomah ABSTRAK Luka diabetik adalah salah satu komplikasi kronis penyakit diabetes melitus yang sangat ditakuti, karena dapat membawa kecacatan seumur hidup bahkan kematian. Jumlah penderita diabetes semakin meningkat. Penelitian ini dilakukan untuk membuktikan efektivitas suplementasi ekstrak daging ikan bujuk dalam mempercepat penyembuhan luka diabetik. Penelitian dilakukan menggunakan tikus putih jantan galur … Read more

Evaluation of Antioxidant and Antidiabetic Activities from Red Seaweed (Eucheuma cottonii) Extract

Vivitri Dewi Prasasty, Benedicta Haryani, Rory Anthony Hutagalung, Noryawati Mulyono, Fatmawati Yazid, Rosmalena Rosmalena, Ernawati Sinaga ABSTRACT Diabetes mellitus is a chronic disorder of metabolic characterized by high blood sugar levels (hyperglycemia) and glucose secretion in urine caused by lack of insulin. Hyperglycemia can cause free radical molecules formation, which can be stabilized by antioxidants. … Read more

Antihyperglycemic and Antihyperlipidemic Effects of Methanolic Seeds Extract of Pandanus odoratissimus in Alloxan-Induced Diabetic Rats

Sri Endarti Rahayu, Ernawati Sinaga, Suprihatin, Arief Dwi Jayanto, Yedi Adistron ABSTRACT Diabetes mellitus is one of the most serious diseases affecting a larger global population, accompanied with other long-term complications. Also, the management is this disease comes with various side effects, hence, the need for substances with little or no side effect. Therefore, this … Read more

Structure-based discovery of novel inhibitors of Mycobacterium tuberculosis CYP121 from Indonesian natural products

Vivitri Dewi Prasasty, Sandra Cindana, Fransiskus Xaverius Ivan, Hilyatuz Zahroh, Ernawati Sinaga ABSTRACT Tuberculosis (TB) continues to be a serious global health threat with the emergence of multidrug-resistant tuberculosis (MDR-TB) and extremely drug-resistant tuberculosis (XDR-TB). There is an urgent need to discover new drugs to deal with the advent of drug-resistant TB variants. This study aims to find new … Read more

Effect of supplementation of Rhodomyrtus tomentosa fruit juice in preventing hypercholesterolemia and atherosclerosis development in rats fed with high fat high cholesterol diet

Ernawati Sinaga, Suprihatin, Yenisbar, Mardian Iswahyudi, Sarwi Setyowati, Vivitri D. Prasasty ABSTRACT Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Nutraceuticals, mainly based on natural products, have been proven to control the risk factors of CVDs effectively. Rhodomyrtus tomentosa is an underutilized fruit that is rich in phenolic compounds and has antioxidant activities. Scientific investigation was needed to … Read more